Article
Neuregulin 1 genetic variation and anterior cingulum integrity in patients with schizophrenia and healthy controls.
Journal of psychiatry & neuroscience : JPN - 1 May 2009
Wang Fei, Jiang Tianzi, Sun Zhiguo, Teng Siew-Leng, Luo Xingguang, Zhu Zhongjun, Zang Yufeng, Zhang Handi, Yue Weihua, Qu Mei, Lu Tianlan, Hong Nan, Huang Haiyan, Blumberg Hilary P, Zhang Dai
Abstract excerpt
BACKGROUND: Neuregulin1 (NRG1) influences the development of white matter connectivity and is implicated in genetic susceptibility to schizophrenia. The cingulum bundle is a white matter structure implicated in schizophrenia. Its anterior component is especially implicated, as it provides reciprocal connections between brain regions with prominent involvement in the disorder. Abnormalities in the structural...
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