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Article

Impact of the genome wide supported NRGN gene on anterior cingulate morphology in schizophrenia.

PloS one - 1 Jan 2012

Ohi Kazutaka, Hashimoto Ryota, Yasuda Yuka, Nemoto Kiyotaka, Ohnishi Takashi, Fukumoto Motoyuki, Yamamori Hidenaga, Umeda-Yano Satomi, Okada Takeya, Iwase Masao, Kazui Hiroaki, Takeda Masatoshi

Abstract excerpt

BACKGROUND: The rs12807809 single-nucleotide polymorphism in NRGN is a genetic risk variant with genome-wide significance for schizophrenia. The frequency of the T allele of rs12807809 is higher in individuals with schizophrenia than in those without the disorder. Reduced immunoreactivity of NRGN, which is expressed exclusively in the brain, has been observed in Brodmann areas (BA) 9 and 32 of the prefrontal...

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Identifiers

PMID: 22253779
DOI: 10.1371/journal.pone.0029780
PMCID: PMC3257237

Genes

NRGN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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