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Article

Genetic Modifiers of Atherosclerosis in Mice

1 Nov 2000

Abstract excerpt

Atherosclerosis is a complex, multifactorial disease with both genetic and environmental determinants. Experimental investigation of the effects of these determinants on the development and progression of atherosclerosis has been greatly facilitated by the use of targeted mouse models of the disease, particularly those resulting from the absence of functional genes for apolipoprotein E or the low density...

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PMID: 11073835
DOI: 10.1161/01.atv.20.11.2336

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