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Article

A quantitative analysis of monochromaticity in genetic interaction networks.

BMC bioinformatics - 1 Jan 2011

Hsu Chien-Hsiang, Wang Tse-Yi, Chu Hsueh-Ting, Kao Cheng-Yan, Chen Kuang-Chi

Abstract excerpt

BACKGROUND: A genetic interaction refers to the deviation of phenotypes from the expected when perturbing two genes simultaneously. Studying genetic interactions help clarify relationships between genes, such as compensation and masking, and identify gene groups of functional modules. Recently, several genome-scale experiments for measuring quantitative (positive and negative) genetic interactions have been...

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PMID: 22372977
DOI: 10.1186/1471-2105-12-S13-S16
PMCID: PMC3278832

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