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Article

Variation in DNA repair gene XRCC3 affects susceptibility to astrocytomas and glioblastomas.

Genetics and molecular research : GMR - 10 Feb 2012

Custódio A C, Almeida L O, Pinto G R, Santos M J, Almeida J R W, Clara C A, Rey J A, Casartelli C

Abstract excerpt

The gene XRCC3 (X-ray cross complementing group 3) has the task of repairing damage that occurs when there is recombination between homologous chromosomes. Repair of recombination between homologous chromosomes plays an important role in maintaining genome integrity, although it is known that double-strand breaks are the main inducers of chromosomal aberrations. Changes in the XRCC3 protein lead to an...

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Source

Identifiers

PMID: 22370935
DOI: 10.4238/2012.February.10.4

Genes

XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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