Article
Association between the Thr241Met polymorphism of X-ray repair cross-complementing group 3 gene and glioma risk: evidence from a meta-analysis based on 4,136 cases and 5,233 controls.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2014
Lin Jun, Kou Yun
Abstract excerpt
Genetic polymorphism of X-ray repair cross-complementing group 3 (XRCC3) Thr241Met has been implicated to alter the risk of glioma, but the results are controversial. Medline, PubMed, Embase, and Cochrane Library databases were independently searched by two investigators up to 13 July 2013. Summary odds ratios (OR) and 95% confidence interval (CI) for Thr241Met polymorphism and prostate cancer were calculated....
Topics
- Alleles
- Brain Neoplasms
- Case-Control Studies
- DNA-Binding Proteins
- Genetic Predisposition to Disease
- Genotype
- Glioma
- Humans
- Odds Ratio
- Polymorphism, Single Nucleotide