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Article

Analysis of the polymorphisms XRCC1Arg194Trp and XRCC1Arg399Gln in gliomas.

Genetics and molecular research : GMR - 14 Jun 2011

Custódio A C, Almeida L O, Pinto G R, Santos M J, Almeida J R W, Clara C A, Rey J A, Casartelli C

Abstract excerpt

XRCC genes (X-ray cross-complementing group) were discovered mainly for their roles in protecting mammalian cells against damage caused by ionizing radiation. Studies determined that these genes are important in the genetic stability of DNA. Although the loss of some of these genes does not necessarily confer high levels of sensitivity to radiation, they have been found to represent important components of...

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PMID: 21710464
DOI: 10.4238/vol10-2gmr1125

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