Article
DNA repair gene XRCC3 variants are associated with susceptibility to glioma in a Chinese population.
Genetics and molecular research : GMR - 8 Sept 2015
Huang J Y, Yang J F, Qu Q, Qu J, Liu F, Liu F E, Xiong T, Lu S H
Abstract excerpt
The susceptibility to glioma is not well understood. It has been suggested that the X-ray cross complementing group 3 (XRCC3) gene influences the capacity to repair DNA damage, leading to increased glioma susceptibility. In this study, we evaluated the relationship between XRCC3 mutations and glioma risk. Genotypes were assessed in 389 Chinese glioma patients and 358 healthy controls. XRCC3 Thr241Met (rs861539)...
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