Article
XRCC1 and XRCC3 variants and risk of glioma and meningioma.
Journal of neuro-oncology - 1 Jun 2008
Kiuru Anne, Lindholm Carita, Heinävaara Sirpa, Ilus Taina, Jokinen Päivi, Haapasalo Hannu, Salminen Tiina, Christensen Helle Collatz, Feychting Maria, Johansen Christoffer, Lönn Stefan, Malmer Beatrice, Schoemaker Minouk J, Swerdlow Anthony J, Auvinen Anssi
Abstract excerpt
Several single nucleotide polymorphisms (SNPs) affecting DNA repair capacity and modifying cancer susceptibility have been described. We evaluated the association of SNPs Arg194Trp, Arg280His, and Arg399Gln in the X-ray cross-complementing group 1 (XRCC1) and Thr241Met in the X-ray cross-complementing group 3 (XRCC3) DNA repair genes with the risk of brain tumors. The Caucasian study population consisted of 701...
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