Article

Conserved roles of GATA4 and its target gene TBX2 in regulation of human cardiogenesis

2025-07-11

Abstract excerpt

The transcription factor (TF) GATA4 is a key mediator of cardiogenesis. GATA4 regulates cardiogenesis through the expression of its target genes, only some of which have been identified. We have used a gain of function model based on pluripotent embryonic ectoderm explants from Xenopus embryos expressing GATA4, to identify a set of downstream targets of GATA4 which are also regulated by Nodal, a known cardiogenic...

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Literature Corpus work: 1c25e0d1-a718-5020-a26c-a073866a0794
DOI: 10.1101/2025.07.11.664341

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Conserved roles of GATA4 and its target gene TBX2 in regulation of human cardiogenesisDOI 10.1101/2025.07.11.664341Read

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