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Article

DMY gene induces male development in genetically female (XX) medaka fish.

Proceedings of the National Academy of Sciences of the United States of America - 6 Mar 2007

Matsuda Masaru, Shinomiya Ai, Kinoshita Masato, Suzuki Aya, Kobayashi Tohru, Paul-Prasanth Bindhu, Lau En-lieng, Hamaguchi Satoshi, Sakaizumi Mitsuru, Nagahama Yoshitaka

Abstract excerpt

Although the sex-determining gene SRY/Sry has been identified in mammals, homologues and genes that have a similar function have yet to be identified in nonmammalian vertebrates. Recently, DMY (the DM-domain gene on the Y chromosome) was cloned from the sex-determining region on the Y chromosome of the teleost fish medaka (Oryzias latipes). DMY has been shown to be required for the normal development of male...

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Share to Animals, Genetically Modified
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, sry

Share to Oryzias

Share to Promoter Regions, Genetic

Share to Sex Determination Processes

Share to Sex Differentiation

Share to X Chromosome

Source

Open in PubMed Open full text

Identifiers

PMID: 17360444
DOI: 10.1073/pnas.0611707104
PMCID: PMC1820675

Genes

SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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DMY gene induces male development in genetically female (XX) medaka fish.PMID 17360444Read ↗

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Wild-derived XY sex-reversal mutants in the Medaka, Oryzias latipes.Semantic proximity Read ↗

Two DM domain genes, <i>DMY</i> and <i>DMRT1</i>, involved in testicular differentiation and development in the medaka, <i>Oryzias latipes</i>Semantic proximity Read ↗

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Dmy initiates masculinity by altering Gsdf/Sox9a2/Rspo1 expression in medaka (Oryzias latipes).Semantic proximity Read ↗

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