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Article

High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions.

Nature medicine - 26 Feb 2012

Di Niro Roberto, Mesin Luka, Zheng Nai-Ying, Stamnaes Jorunn, Morrissey Michael, Lee Jane-Hwei, Huang Min, Iversen Rasmus, du Pré M Fleur, Qiao Shuo-Wang, Lundin Knut E A, Wilson Patrick C, Sollid Ludvig M

Abstract excerpt

Celiac disease is an immune-mediated disorder in which mucosal autoantibodies to the enzyme transglutaminase 2 (TG2) are generated in response to the exogenous antigen gluten in individuals who express human leukocyte antigen HLA-DQ2 or HLA-DQ8 (ref. 3). We assessed in a comprehensive and nonbias...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22366952
DOI: 10.1038/nm.2656
PMCID: PMC4533878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22366952-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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