Article
Cryptic genetic gluten intolerance revealed by intestinal antitransglutaminase antibodies and response to gluten-free diet.
Gut - 1 Nov 2011
Not Tarcisio, Ziberna Fabiana, Vatta Serena, Quaglia Sara, Martelossi Stefano, Villanacci Vincenzo, Marzari Roberto, Florian Fiorella, Vecchiet Monica, Sulic Ana-Marija, Ferrara Fortunato, Bradbury Andrew, Sblattero Daniele, Ventura Alessandro
Abstract excerpt
BACKGROUND AND OBJECTIVE: Antitransglutaminase (anti-TG2) antibodies are synthesised in the intestine and their presence seems predictive of future coeliac disease (CD). This study investigates whether mucosal antibodies represent an early stage of gluten intolerance even in the absence of intestinal damage and serum anti-TG2 antibodies. METHODS: This study investigated 22 relatives of patients with CD...
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