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Article

Proteomics of mouse BRCA1-deficient mammary tumors identifies DNA repair proteins with potential diagnostic and prognostic value in human breast cancer.

Molecular & cellular proteomics : MCP - 1 Jul 2012

Warmoes Marc, Jaspers Janneke E, Pham Thang V, Piersma Sander R, Oudgenoeg Gideon, Massink Maarten P G, Waisfisz Quinten, Rottenberg Sven, Boven Epie, Jonkers Jos, Jimenez Connie R

Abstract excerpt

Breast cancer 1, early onset (BRCA1) hereditary breast cancer, a type of cancer with defects in the homology-directed DNA repair pathway, would benefit from the identification of proteins for diagnosis, which might also be of potential use as screening, prognostic, or predictive markers. Sporadic breast cancers with defects in the BRCA1 pathway might also be diagnosed. We employed proteomics based on...

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Identifiers

PMID: 22366898
DOI: 10.1074/mcp.M111.013334
PMCID: PMC3394939

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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