Network modeling links breast cancer susceptibility and centrosome dysfunction.

doi:10.1038/ng.2007.2

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Article

Network modeling links breast cancer susceptibility and centrosome dysfunction.

Nature genetics - 1 Nov 2007

Pujana Miguel Angel, Han Jing-Dong J, Starita Lea M, Stevens Kristen N, Tewari Muneesh, Ahn Jin Sook, Rennert Gad, Moreno Víctor, Kirchhoff Tomas, Gold Bert, Assmann Volker, Elshamy Wael M, Rual Jean-François, Levine Douglas, Rozek Laura S, Gelman Rebecca S, Gunsalus Kristin C, Greenberg Roger A, Sobhian Bijan, Bertin Nicolas, Venkatesan Kavitha, Ayivi-Guedehoussou Nono, Solé Xavier, Hernández Pilar, Lázaro Conxi, Nathanson Katherine L, Weber Barbara L, Cusick Michael E, Hill David E, Offit Kenneth, Livingston David M, Gruber Stephen B, Parvin Jeffrey D, Vidal Marc

Abstract excerpt

Many cancer-associated genes remain to be identified to clarify the underlying molecular mechanisms of cancer susceptibility and progression. Better understanding is also required of how mutations in cancer genes affect their products in the context of complex cellular networks. Here we have used...

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Identifiers

PMID: 17922014
DOI: 10.1038/ng.2007.2

Genes

HMMR
BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17922014-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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