Article
Generalized T2 test for genome association studies.
American journal of human genetics - 1 May 2002
Xiong Momiao, Zhao Jinying, Boerwinkle Eric
Abstract excerpt
Recent progress in the development of single-nucleotide polymorphism (SNP) maps within genes and across the genome provides a valuable tool for fine-mapping and has led to the suggestion of genomewide association studies to search for susceptibility loci for complex traits. Test statistics for genome association studies that consider a single marker at a time, ignoring the linkage disequilibrium between markers,...
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