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Article

Genetic epidemiology and heritability of AIS: A study of 415 Chinese female patients.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Sept 2012

Tang Nelson L S, Yeung Hiu-Yan, Hung Vivian W Y, Di Liao Chen, Lam Tsz-Ping, Yeung Hau-Man, Lee Kwong-Man, Ng Bobby Kin-Wah, Cheng Jack Chun-Yiu

Abstract excerpt

Recent familial segregation studies supported a multifactorial genetic model for the etiology of adolescent idiopathic scoliosis (AIS). However, the extent of quantitative genetic effects, such as heritability, have not been fully evaluated. This genetic epidemiology study examined the sibling recurrent risk and heritability of AIS in first-degree relatives of 415 Chinese female patients, which is up to now the...

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PMID: 22362628
DOI: 10.1002/jor.22090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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