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Article

Epidemiological survey of idiopathic scoliosis and sequence alignment analysis of multiple candidate genes.

International orthopaedics - 1 Jun 2012

Yang Tao, Jia Quanzhang, Guo Hong, Xu Jianzhong, Bai Yun, Yang Kai, Luo Fei, Zhang Zehua, Hou Tianyong

Abstract excerpt

PURPOSE: To investigate the effects of genetic factors on idiopathic scoliosis (IS) and genetic modes through genetic epidemiological survey on IS in Chongqing City, China, and to determine whether SH3GL1, GADD45B, and FGF22 in the chromosome 19p13.3 are the pathogenic genes of IS through genetic sequence analysis. METHODS: 214 nuclear families were investigated to analyse the age incidence, familial aggregation,...

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Source

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Identifiers

PMID: 22183150
DOI: 10.1007/s00264-011-1419-z
PMCID: PMC3353077

Genes

FGF22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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