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Article

Genetic Variant of PAX1 Gene Is Functionally Associated With Adolescent Idiopathic Scoliosis in the Chinese Population.

Spine - 1 Apr 2018

Xu Leilei, Sheng Fei, Xia Chao, Qin Xiaodong, Tang Nelson Leung-Sang, Qiu Yong, Cheng Jack Chun-Yiu, Zhu Zezhang

Abstract excerpt

STUDY DESIGN: A genetic association study. OBJECTIVE: To investigate the association between PAX1 gene and the susceptibility of adolescent idiopathic scoliosis (AIS) in the Chinese population and to further determine the functional variant regulating PAX1 expression in patients with AIS. SUMMARY OF BACKGROUND DATA: In a previous study an enhancer locus of PAX1 was reported to be associated with the development...

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Source

Identifiers

PMID: 29095406
DOI: 10.1097/BRS.0000000000002475

Genes

PAX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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