Article
Polygenic inheritance of adolescent idiopathic scoliosis: a study of extended families in Utah.
American journal of medical genetics. Part A - 1 May 2010
Ward Kenneth, Ogilvie James, Argyle Veeann, Nelson Lesa, Meade Mary, Braun John, Chettier Rakesh
Abstract excerpt
A heritability study of 69 extended Utah families with a history of adolescent idiopathic scoliosis (AIS) indicates that AIS is a polygenic, multifactorial condition. Each family reported a history of AIS within four generations; a total of 247 individuals were confirmed via X-rays and medical re...
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