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Article

Possible association between autism and variants in the brain-expressed tryptophan hydroxylase gene (TPH2).

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 May 2005

Coon Hilary, Dunn Diane, Lainhart Janet, Miller Judith, Hamil Cindy, Battaglia Agatino, Tancredi Raffaella, Leppert Mark F, Weiss Robert, McMahon William

Abstract excerpt

We report a possible association between autism in our sample and a recently described brain-expressed tryptophan hydroxylase gene (TPH2). The well-replicated involvement of the serotonin neurotransmitter system in autism has stimulated interest in many genes in the serotonin pathway as possible...

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Source

Identifiers

PMID: 15768392
DOI: 10.1002/ajmg.b.30168

Genes

TPH2
TPH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15768392-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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