Article
The Amerindian mtDNA haplogroup B2 enhances the risk of HPV for cervical cancer: de-regulation of mitochondrial genes may be involved.
Journal of human genetics - 1 Apr 2012
Guardado-Estrada Mariano, Medina-Martínez Ingrid, Juárez-Torres Eligia, Roman-Bassaure Edgar, Macías Luis, Alfaro Ana, Alcántara-Vázquez Avissai, Alonso Patricia, Gomez Guillermo, Cruz-Talonia Fernando, Serna Luis, Muñoz-Cortez Sergio, Borges-Ibañez Manuel, Espinosa Ana, Kofman Susana, Berumen Jaime
Abstract excerpt
Although human papillomavirus (HPV) infection is the main causal factor for cervical cancer (CC), there are data suggesting that genetic factors could modulate the risk for CC. Sibling studies suggest that maternally inherited factors could be involved in CC. To assess whether mitochondrial DNA (...
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