Article
Assessing the utility of three TaqMan probes for the diagnosis of tuberculosis and resistance to rifampin and isoniazid in Veracruz, México.
Canadian journal of microbiology - 1 Mar 2012
Zenteno-Cuevas Roberto, Cuevas-Cordoba Betzaida, Enciso Antonio, Enciso Leonor, Cuellar Aremy
Abstract excerpt
Mutations at codons 526 and 531 in the rpoB gene and at 315 in the katG gene are considered diagnostic markers for resistance to rifampin and isoniazid in tuberculosis. The aim of this study was to design and evaluate three TaqMan probes for the identification of these mutations in 138 respiratory samples positive for acid-fast bacilli, and 32 clinical isolates from a region with considerable levels of drug...
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