Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel dual probe-based method for mutation detection using isothermal amplification.

PloS one - 1 Jan 2024

Nandu Nidhi, Miller Michael, Tong Yanhong, Lu Zhi-Xiang

Abstract excerpt

Cost efficient and rapid detection tools to detect mutations especially those linked to drug-resistance are important to address concerns of the rising multi-drug resistance infections. Here we integrated dual probes, namely a calibrator probe and an indicator probe, into isothermal amplification detection system. These two probes are designed to bind distinct regions on the same amplicon to determine the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon
Share to DNA-Directed RNA Polymerases
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Diagnostic Techniques

Share to Mycobacterium tuberculosis

Share to Nucleic Acid Amplification Techniques

Share to Rifampin

Share to Tuberculosis, Multidrug-Resistant

Source

Open in PubMed Open full text

Identifiers

PMID: 39436873
DOI: 10.1371/journal.pone.0309541
PMCID: PMC11495626

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel dual probe-based method for mutation detection using isothermal amplification.PMID 39436873Read ↗

Single Isothermal Assay for Multi-Site Mutation Detection of Rifampicin Resistance in Mycobacterium tuberculosis.Semantic proximity Read ↗

Rapid and Ultrasensitive Approach for the Simultaneous Detection of Multilocus Mutations to Distinguish Rifampicin-Resistant Mycobacterium tuberculosis.Semantic proximity Read ↗

In silico evaluation of WHO-endorsed molecular methods to detect drug resistant tuberculosisSemantic proximity Read ↗

In silico evaluation of WHO-endorsed molecular methods to detect drug resistant tuberculosis.Semantic proximity Read ↗

Dual-Probe Assay for Rapid Detection of Drug-Resistant Mycobacterium tuberculosis by Real-Time PCRSemantic proximity Read ↗

Rapid Identification of High-Prevalence Drug-Resistant Mutations in Mycobacterium tuberculosis Using a Portable Colorimetric Array.Semantic proximity Read ↗

Analytical performance of a multi-target open real-time PCR assay for simultaneous detection of tuberculosis, non-tuberculous mycobacteria, and drug resistance in a high-burden settingSemantic proximity Read ↗

Accurate and affordable detection of rifampicin and isoniazid resistance in Tuberculosis sputum specimens by multiplex PCR-multiple probes melting analysis.Semantic proximity Read ↗

Development of a single multiplex amplification refractory mutation system PCR for the detection of rifampin-resistant Mycobacterium tuberculosis.Semantic proximity Read ↗

Multi-Fluorescence Real-Time PCR Assay for Detection of RIF and INH Resistance of M. tuberculosisSemantic proximity Read ↗

Multiplex real-time PCR melting curve assay to detect drug-resistant mutations of Mycobacterium tuberculosis.Semantic proximity Read ↗

Detection of rifampin resistance in Mycobacterium tuberculosis in a single tube with molecular beacons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.