Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modelling age-related metabolic disorders in the mouse.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2014

Goldsworthy Michelle E, Potter Paul K

Abstract excerpt

Ageing can be characterised by a general decline in cellular function, which affects whole-body homoeostasis with metabolic dysfunction-a common hallmark of ageing. The identification and characterisation of the genetic pathways involved are paramount to the understanding of how we age and the development of therapeutic strategies for combating age-related disease. Furthermore, in addition to understanding the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Aging
Share to Diabetes Mellitus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammation

Share to Insulin

Share to Metabolic Diseases

Share to Mitochondria

Share to Obesity

Source

Open in PubMed Open full text

Identifiers

PMID: 25118634
DOI: 10.1007/s00335-014-9539-6
PMCID: PMC4164835

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modelling age-related metabolic disorders in the mouse.PMID 25118634Read ↗

Mouse models of ageing and their relevance to diseaseSemantic proximity Read ↗

Mouse phenogenomics: the fast track to "systems metabolism".Semantic proximity Read ↗

The metabolic footprint of aging in miceSemantic proximity Read ↗

Ageing-associated phenotypes in mice.Semantic proximity Read ↗

Growth factor, energy and nutrient sensing signalling pathways in metabolic ageingSemantic proximity Read ↗

Mouse models of peripheral metabolic disease.Semantic proximity Read ↗

Targeting metabolic pathways for extension of lifespan and healthspan across multiple species.Semantic proximity Read ↗

Mice as a Mammalian Model for Research on the Genetics of AgingSemantic proximity Read ↗

Aging and genome maintenance: lessons from the mouse?Semantic proximity Read ↗

How do metabolic processes age: Evidence from human metabolomic studiesSemantic proximity Read ↗

Daily rhythms in metabolic and locomotor behaviour of prematurely ageing PolgA miceSemantic proximity Read ↗

Generation and Identification of Mutations Resulting in Chronic and Age-Related Phenotypes in Mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.