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Article

Next generation sequencing has lower sequence coverage and poorer SNP-detection capability in the regulatory regions.

Scientific reports - 1 Jan 2011

Wang Weixin, Wei Zhi, Lam Tak-Wah, Wang Junwen

Abstract excerpt

The rapid development of next generation sequencing (NGS) technology provides a new chance to extend the scale and resolution of genomic research. How to efficiently map millions of short reads to the reference genome and how to make accurate SNP calls are two major challenges in taking full adva...

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PMID: 22355574
DOI: 10.1038/srep00055
PMCID: PMC3216542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22355574-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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