Article

Uncovering missed indels by leveraging unmapped reads

2018-12-07

Abstract excerpt

In current practice, Next Generation Sequencing (NGS) applications start with mapping/aligning short reads to the reference genome, with the aim of identifying genetic mutations. While most short reads can be mapped to the reference genome accurately by existing alignment tools, a significant number remain unmapped and excluded from downstream analyses thus potentially discarding important biological information h...

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Literature Corpus work: 3ba79489-1fe7-5c44-82cf-714ca71618c2
DOI: 10.1101/488601

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