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Article

Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving.

Proceedings of the National Academy of Sciences of the United States of America - 6 Mar 2012

Varadarajan Navin, Kwon Douglas S, Law Kenneth M, Ogunniyi Adebola O, Anahtar Melis N, Richter James M, Walker Bruce D, Love J Christopher

Abstract excerpt

The nature of certain clinical samples (tissue biopsies, fluids) or the subjects themselves (pediatric subjects, neonates) often constrain the number of cells available to evaluate the breadth of functional T-cell responses to infections or therapeutic interventions. The methods most commonly used to assess this functional diversity ex vivo and to recover specific cells to expand in vitro usually require more...

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PMID: 22355106
DOI: 10.1073/pnas.1111205109
PMCID: PMC3309713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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