Article
Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47.
Molecular and cellular biology - 1 May 2012
Teachenor Robert, Beck Kristina, Wright Lilyan Y T, Shen Zhouxin, Briggs Steven P, Murre Cornelis
Abstract excerpt
Numerous in vitro as well as genetic studies have demonstrated that the activities of the E2A proteins are regulated at multiple levels, including modulation of DNA binding by the Id proteins, association with the transcriptional modulators p300 and ETO, and posttranslational modifications. Here, we use affinity purification of tagged E47 combined with mass spectrometry in order to show that E47 interacts with...
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