Article
IL28B polymorphism is associated with fatty change in the liver of chronic hepatitis C patients.
Journal of gastroenterology - 1 Jul 2012
Ohnishi Mayu, Tsuge Masataka, Kohno Tomohiko, Zhang Yizhou, Abe Hiromi, Hyogo Hideyuki, Kimura Yuki, Miki Daiki, Hiraga Nobuhiko, Imamura Michio, Takahashi Shoichi, Ochi Hidenori, Hayes C Nelson, Tanaka Shinji, Arihiro Koji, Chayama Kazuaki
Abstract excerpt
BACKGROUND: Several single nucleotide polymorphisms (SNPs) within the interleukin 28B (IL28B) locus are associated with sustained viral response in chronic hepatitis C (HCV) patients who were treated with pegylated interferon (PEG-IFN) plus ribavirin (RBV) combination therapy. Recently, an association between γ-GTP level and IL28B genotype was identified. In this study, the relationship between IL28B genotype and...
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