Invited commentary: more surprises from a gene desert.

Abstract excerpt

Pleiotropy across the 8q24 region is perhaps the most intriguing of the genome-wide association findings relating to cancer. This region of chromosome 8 is a gene desert, far from any recognized genes. Guarrera et al., whose work is reported in this issue (Am J Epidemiol. 2012;175(6):479-487), took an epidemiologic approach to learn more about the 8q24 region. They capitalized on their ascertainment of other...

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