Article
Integrative epidemiology: from risk assessment to outcome prediction.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Jan 2005
Spitz Margaret R, Wu Xifeng, Mills Gordon
Abstract excerpt
In this paper, we advance the concept of integrative epidemiology. Our unifying premise is that the same genes that are implicated in cancer risk may also be involved in a person's propensity to carcinogenic exposure and/or to modulation of therapeutic outcome. In the coming years, molecular epidemiology will play an increasingly prominent role in early detection of cancer and in identifying genetically high-risk...
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