Article
Association between total number of deaths, diabetes mellitus, incident cancers, and haplotypes in chromosomal region 8q24 in a prospective study.
American journal of epidemiology - 15 Mar 2012
Guarrera Simonetta, Ricceri Fulvio, Polidoro Silvia, Sacerdote Carlotta, Allione Alessandra, Rosa Fabio, Voglino Floriana, Critelli Rossana, Russo Alessia, Vineis Paolo, Matullo Giuseppe
Abstract excerpt
The 8q24 region is a gene desert, although chromosomal aberrations and somatic amplification involving this region, including translocations involving the protooncogene c-MYC, have been frequently reported in people with cancer. To investigate the role of variants in 8q24 region, the authors analyzed data from a prospective study (n = 10,372 participants who were followed for 11 years) in which a large number of...
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