SNCA rs3822086 C>T Polymorphism Increases the Susceptibility to Parkinson's Disease in a Chinese Han Population.

doi:10.1089/gtmb.2015.0046

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SNCA rs3822086 C>T Polymorphism Increases the Susceptibility to Parkinson's Disease in a Chinese Han Population.

Genetic testing and molecular biomarkers - 1 Sept 2015

Jian Chong-Dong, Huang Jian-Min, Meng Lan-Qing, Li Xue-Bin, Huang Rui-Ya, Shi Sheng-Liang, Wu Yuan, Qin Chao, Chen Jin, Zhang Yan-Mei, Wang Shuang, Feng Yin-Ling, Zhou Sheng-Nian

Abstract excerpt

OBJECTIVE: Protofibrils of alpha-synuclein mediate neuronal cell death and propagate Parkinson's disease (PD). In this study, we investigated the relationship between the rs3822086 C>T polymorphism located in the fourth intron of the alpha-synuclein (SNCA) gene and susceptibility to PD in a Chinese Han population. METHODS: 146 PD patients and 144 sex- and age-matched healthy individuals (control group) were...

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PMID: 26203864
DOI: 10.1089/gtmb.2015.0046

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SNCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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