Article
Genetic variation in CYP2A6 predicts neural reactivity to smoking cues as measured using fMRI.
NeuroImage - 1 May 2012
Tang Deborah W, Hello Brian, Mroziewicz Margaret, Fellows Lesley K, Tyndale Rachel F, Dagher Alain
Abstract excerpt
Smoking cues trigger craving for cigarettes and relapse. Nicotine metabolism, mediated by the enzyme CYP2A6, also influences smoking behavior. In this study, we investigated how nicotine metabolism and genetic variation in CYP2A6 influence the neural response to smoking cues in humans using funct...
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