Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association analysis of brain-derived neurotrophic factor Val66Met polymorphisms with Alzheimer's disease and age of onset.

Neuropsychobiology - 1 Jan 2004

Tsai Shih-Jen, Hong Chen-Jee, Liu Hsiu-Chih, Liu Tsung-Yun, Hsu Li-En, Lin Ching-Hua

Abstract excerpt

Because of a decrease in central brain-derived neurotrophic factor (BDNF) levels in Alzheimer's disease (AD) and the important role of BDNF in neuronal survival, BDNF may represent a candidate gene conferring susceptibility to AD. Recently, a functional BDNF Val66Met polymorphism has been associated with AD in an Italian population. In the present study, we investigated a possible role of this BDNF polymorphism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain-Derived Neurotrophic Factor

Share to Case-Control Studies

Share to DNA Mutational Analysis

Share to Gene Frequency

Share to Methionine

Share to Valine

Source

Identifiers

PMID: 14730194
DOI: 10.1159/000075332

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association analysis of brain-derived neurotrophic factor Val66Met polymorphisms with Alzheimer's disease and age of onset.PMID 14730194Read ↗

Lack of association between the BDNF gene Val66Met polymorphism and Alzheimer disease in a Chinese Han population.Semantic proximity Read ↗

Brain derived neurotrophic factor Val66Met polymorphism and psychotic symptoms in Alzheimer's disease.Semantic proximity Read ↗

Val66Met Polymorphism in BDNF Has No Sexual and APOE ε4 Status-Based Dimorphic Effects on Susceptibility to Alzheimer's Disease: Evidence From an Updated Meta-Analysis of Case-Control Studies and High-Throughput Genotyping Cohorts.Semantic proximity Read ↗

Association analysis of brain-derived neurotrophic factor (BDNF) gene 196 A/G polymorphism with Alzheimer's disease (AD) in mainland Chinese.Semantic proximity Read ↗

Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in Parkinson's disease and age of onset.Semantic proximity Read ↗

Role of BDNF Val66Met functional polymorphism in Alzheimer's disease-related depression.Semantic proximity Read ↗

Polymorphism at codon 66 of the brain-derived neurotrophic factor gene is not associated with sporadic Alzheimer's disease.Semantic proximity Read ↗

The study of BDNF Val66Met polymorphism in Chinese schizophrenic patients.Semantic proximity Read ↗

Investigation of the effect of brain-derived neurotrophic factor (BDNF) polymorphisms on the risk of late-onset Alzheimer's disease (AD) and quantitative measures of AD progression.Semantic proximity Read ↗

Val66Met polymorphism and BDNF levels in Alzheimer's disease patients in North Indian population.Semantic proximity Read ↗

Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism in schizophrenia is associated with age at onset and symptoms.Semantic proximity Read ↗

The brain-derived neurotrophic factor gene as a possible susceptibility candidate for Alzheimer's disease in a chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.