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Article

BDNF Val66Met homozygosity does not influence plasma BDNF levels in healthy human subjects.

Progress in neuro-psychopharmacology & biological psychiatry - 3 Jun 2013

Luykx Jurjen J, Boks Marco P M, Breetvelt Elemi J, Aukes Maartje F, Strengman Eric, da Pozzo Eleonora, Dell'osso Liliana, Marazziti Donatella, van Leeuwen Annelies, Vreeker Annabel, Abramovic Lucija, Martini Claudia, Numans Mattijs E, Kahn René S, Ophoff Roel A

Abstract excerpt

A putative pathway by which the BDNF Val66Met polymorphism (rs6265) leads to aberrant phenotypes is its influence on plasma BDNF. Research into the impact of rs6265 on plasma BDNF has given rise to conflicting results. Moreover, most such studies have compared Met-carriers with Val-homozygous subjects. We therefore genotyped subjects from a population-based cohort (the Utrecht Health Project, N=2743) and assessed...

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Identifiers

PMID: 23269345
DOI: 10.1016/j.pnpbp.2012.12.017

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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