Article
Hypermethylation of suppressor of cytokine signaling 1 in hepatocellular carcinoma patients.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Saelee Pensri, Chuensumran Ubol, Wongkham Sopit, Chariyalertsak Sunanta, Tiwawech Danai, Petmitr Songsak
Abstract excerpt
Hepatocellular carcinoma (HCC), the most common primary hepatic tumor, is highly prevalent in the Asia-Pacific region, including Thailand. Many genetic and epigenetic alterations in HCC have been elucidated. The aim of this study was to determine whether aberrant methylation of the suppressor of cytokine signaling 1 gene (SOCS1) occurs in HCCs. Methylation specific-PCR assays were performed to identify the...
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