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Article

Prediction of potential NS3-based T cell epitopes of hepatitis C virus by in-silico and in-vitro approach.

Scientific reports - 28 Apr 2026

Dutta Supradip, Dhar Amlanjyoti, Pande Meghamala, Ghose Ankita, Majumdar Moumita, Bakshi Sagnik, Das Raina, Nath Shreyasi, Ghosh Anwesha, Sadhukhan Provash Chandra

Abstract excerpt

Due to the absence of an effective vaccine and suboptimal responses to direct-acting antivirals (DAA), Hepatitis C virus (HCV) genotype 3-prevalent in South Asia, the Middle East, and Central Asia-remains a significant public health challenge. This study aimed to identify conserved NS3-based T-cell epitopes of HCV genotype 3 using an integrated in-silico and in-vitro approach. NS3 sequences from 36 HCV-3a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42050322
DOI: 10.1038/s41598-026-49711-9
PMCID: PMC13315738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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