Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of population diversity on the prediction of 7-SNP NAT2 phenotypes using the tagSNP rs1495741 or paired SNPs.

Pharmacogenetics and genomics - 1 Apr 2012

Suarez-Kurtz Guilherme, Sortica Vinicius A, Vargens Daniela D, Bruxel Estela M, Petzl-Erler Maria-Luiza, Petz-Erler Maria-Luiza, Tsuneto Luisa T, Hutz Mara H

Abstract excerpt

A novel NAT2 tagSNP (rs1495741) and a 2-SNP genotype (rs1041983 and rs1801280) have been recently shown to accurately predict the NAT2 acetylator phenotypes in populations of exclusive or predominant European/White ancestry. We confirmed the accuracy of the tagSNP approach in White Brazilians, bu...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylation
Share to Africa South of the Sahara
Share to Arylamine N-Acetyltransferase
Share to Black People
Share to Brazil
Share to HapMap Project
Share to Predictive Value of Tests
Share to White People

Source

Identifiers

PMID: 22336957
DOI: 10.1097/FPC.0b013e3283519c7c

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22336957-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of population diversity on the prediction of 7-SNP NAT2 phenotypes using the tagSNP rs1495741 or paired SNPs.PMID 22336957Read ↗

Single nucleotide polymorphism coverage and inference of N-acetyltransferase-2 acetylator phenotypes in wordwide population groups.Semantic proximity Read ↗

Novel tagging SNP rs1495741 and 2-SNPs (rs1041983 and rs1801280) yield a high prediction of the NAT2 genotype in HapMap samples.Semantic proximity Read ↗

Genotyping NAT2 with only two SNPs (rs1041983 and rs1801280) outperforms the tagging SNP rs1495741 and is equivalent to the conventional 7-SNP NAT2 genotype.Semantic proximity Read ↗

NAT2 global landscape: Genetic diversity and acetylation statuses from a systematic review.Semantic proximity Read ↗

The differential effect of NAT2 variant alleles permits refinement in phenotype inference and identifies a very slow acetylation genotype.Semantic proximity Read ↗

Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene.Semantic proximity Read ↗

Worldwide distribution of NAT2 diversity: implications for NAT2 evolutionary history.Semantic proximity Read ↗

Determination of NAT2 acetylation status in the Greenlandic population.Semantic proximity Read ↗

Differential distribution of NAT2 polymorphisms and NAT2 acetylator phenotypes among indigenous populations of the Brazilian Amazon.Semantic proximity Read ↗

NAT2 sequence polymorphisms and acetylation profiles in Indians.Semantic proximity Read ↗

Analysis of nucleotide diversity of NAT2 coding region reveals homogeneity across Native American populations and high intra-population diversity.Semantic proximity Read ↗

A single nucleotide polymorphism tags variation in the arylamine N-acetyltransferase 2 phenotype in populations of European background.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.