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Differential distribution of NAT2 polymorphisms and NAT2 acetylator phenotypes among indigenous populations of the Brazilian Amazon.

Pharmacogenetics and genomics - 1 Dec 2024

Perini Jamila A, Basta Paulo C, Cardoso Jessica V, Elias Anna Beatriz R, Suarez-Kurtz Guilherme

Abstract excerpt

OBJECTIVES: We report, for the first time, the distribution of four no-function NAT2 single nucleotide polymorphisms and inferred NAT2 acetylator phenotypes in three indigenous groups (Munduruku, Paiter-Suruí, and Yanomami), living in reservation areas in the Brazilian Amazon. METHODS: Two hundred and seventy-six participants from three indigenous groups (92 for each group) were included and genotyped for four...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39259702
DOI: 10.1097/FPC.0000000000000544

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