Association of genetic polymorphisms in MDM2, PTEN and P53 with risk of esophageal squamous cell carcinoma.

doi:10.1038/jhg.2012.15

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Article

Association of genetic polymorphisms in MDM2, PTEN and P53 with risk of esophageal squamous cell carcinoma.

Journal of human genetics - 1 Apr 2012

Ma Juan, Zhang Jianna, Ning Tao, Chen Ziping, Xu Changqing

Abstract excerpt

Genetic variations in MDM2, PTEN and P53 might be involved in cancer susceptibility. To assess the contribution of polymorphisms in these three genes to the risk of esophageal squamous cell carcinoma (ESCC) in a Chinese population, we genotyped MDM2 T309G, Del1518, PTEN rs701848, rs2735343 and P5...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, p53

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Share to Polymorphism, Restriction Fragment Length

Share to Proto-Oncogene Proteins c-mdm2

Share to PTEN Phosphohydrolase

Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 22336889
DOI: 10.1038/jhg.2012.15

Genes

PTEN
MDM2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22336889-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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