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Article

Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.

Pigment cell research - 1 Aug 2006

Hoek Keith S, Schlegel Natalie C, Brafford Patricia, Sucker Antje, Ugurel Selma, Kumar Rajiv, Weber Barbara L, Nathanson Katherine L, Phillips David J, Herlyn Meenhard, Schadendorf Dirk, Dummer Reinhard

Abstract excerpt

The molecular biology of metastatic potential in melanoma has been studied many times previously and changes in the expression of many genes have been linked to metastatic behaviour. What is lacking is a systematic characterization of the regulatory relationships between genes whose expression is related to metastatic potential. Such a characterization would produce a molecular taxonomy for melanoma which could...

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Identifiers

PMID: 16827748
DOI: 10.1111/j.1600-0749.2006.00322.x

Genes

BRAF
NRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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