Article

LRSim: a Linked Reads Simulator generating insights for better genome partitioning

2017-01-26

Abstract excerpt

<h4>Motivation</h4> Linked reads are a form of DNA sequencing commercialized by 10X Genomics that uses highly multiplexed barcoding within microdroplets to tag short reads to progenitor molecules. The linked reads, spanning tens to hundreds of kilobases, offer an alternative to long-read sequencing for de novo assembly, haplotype phasing and other applications. However, there is no available simulator, making it...

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Literature Corpus work: 55d4c59a-6824-5668-a4bc-15ca8b042fec
DOI: 10.1101/103549

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