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Article

Discovery of <i>ALK</i>‐<i>PTPN3</i> gene fusion from human non‐small cell lung carcinoma cell line using next generation RNA sequencing

15 Feb 2012

Abstract excerpt

An increasing number of chromosomal aberrations is being identified in solid tumors providing novel biomarkers for various types of cancer and new insights into the mechanisms of carcinogenesis. We applied next generation sequencing technique to analyze the transcriptome of the non-small cell lung carcinoma (NSCLC) cell line H2228 and discovered a fusion transcript composed of multiple exons of ALK (anaplastic...

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PMID: 22334442
DOI: 10.1002/gcc.21945

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