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Molecular characteristics and clinical outcomes of complex ALK rearrangements identified by next-generation sequencing in non-small cell lung cancers

2021-03-03

Abstract excerpt

<title>Abstract</title> <p>Background Complex kinase rearrangement, a mutational process involving one or two chromosomes with clustered rearrangement breakpoints, interferes with the accurate detection of kinase fusions by DNA-based next-generation sequencing (NGS). We investigated the characteristics of complex <italic>ALK</italic> rearrangements in non-small cell lung cancers using multiple molecular tests. M...

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Literature Corpus work
bdd8bb0a-4063-56fe-9137-4bab79958183
DOI
10.21203/rs.3.rs-273496/v1
Open publication

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Molecular characteristics and clinical outcomes of complex ALK rearrangements identified by next-generation sequencing in non-small cell lung cancersDOI 10.21203/rs.3.rs-273496/v1
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