Article
Y Chromosome, Hypertension and Cardiovascular Disease: Is Inflammation the Answer?
13 Jun 2019
Abstract excerpt
It is now becomingly increasingly evident that the functions of the mammalian Y chromosome are not circumscribed to the induction of male sex. While animal studies have shown variations in the Y are strongly accountable for blood pressure (BP), this is yet to be confirmed in humans. We have recently shown modulation of adaptive immunity to be a significant mechanism underpinning Y-chromosome-dependent differences...
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