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Article

Identification of activated cryptic 5' splice sites using structure profiles and odds measure.

Nucleic acids research - 1 May 2012

Tsai Kun-Nan, Wang Daryi

Abstract excerpt

The activation of cryptic 5' splice sites (5' SSs) is often related to human hereditary diseases. The DNA-based mutation screening strategies are commonly used to recognize the cryptic 5' SSs, because features of the local DNA sequence can influence the choice of cryptic 5' SSs. To improve the identification of the cryptic 5' SSs, we developed a structure-based method, named SPO (structure profiles and odds...

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Identifiers

PMID: 22323516
DOI: 10.1093/nar/gks061
PMCID: PMC3378896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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