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Article

Intrinsic differences between authentic and cryptic 5' splice sites.

Nucleic acids research - 1 Nov 2003

Roca Xavier, Sachidanandam Ravi, Krainer Adrian R

Abstract excerpt

Cryptic splice sites are used only when use of a natural splice site is disrupted by mutation. To determine the features that distinguish authentic from cryptic 5' splice sites (5'ss), we systematically analyzed a set of 76 cryptic 5'ss derived from 46 human genes. These cryptic 5'ss have a similar frequency distribution in exons and introns, and are usually located close to the authentic 5'ss. Statistical...

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Identifiers

PMID: 14576320
DOI: 10.1093/nar/gkg830
PMCID: PMC275472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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