Article
Forgetting is regulated via Musashi-mediated translational control of the Arp2/3 complex.
Cell - 13 Mar 2014
Hadziselimovic Nils, Vukojevic Vanja, Peter Fabian, Milnik Annette, Fastenrath Matthias, Fenyves Bank Gabor, Hieber Petra, Demougin Philippe, Vogler Christian, de Quervain Dominique J-F, Papassotiropoulos Andreas, Stetak Attila
Abstract excerpt
A plastic nervous system requires the ability not only to acquire and store but also to forget. Here, we report that musashi (msi-1) is necessary for time-dependent memory loss in C. elegans. Tissue-specific rescue demonstrates that MSI-1 function is necessary in the AVA interneuron. Using RNA-bi...
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